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      Adenovirus Rapid Tests

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      Adenovirus Rapid Tests


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      SUMMARY

      Acute diarrhea disease in young children is a major cause of morbidity worldwide and is a leading cause of mortality in developing countries.Research has shown that enteric adenoviruses,primarily Ad40 and Ad41,are a leading cause of diarrhea in many of these children,second only to the rotaviruses.2,3,4These viral pathogens have been isolated throughout the world,and can cause diarrhea in children year round.Infections patients of all ages.Further studies indicate that adenoviruses are associated with 4-15% of all hospitalized cases of viral gastroenteritis.1,2,3,4,5

      Rapid and accurate diagnosis of gastroenteritis due to adenovirus is helpful in establishing the etiology of gastroenteritis and related patient management.Other diagnostic techniques such as electron microscopy(EM)and nucleic acid hybridization are expensive and labor-intensive.With the self-limiting nature of adenovirus infection,such expensive and labor-intensive tests may not be necessary.

      The Adenovirus Rapid Test Device is a rapid chromatographic immunoassay for the qualitative detection of adenovirus in human feces specimen,providing results in10 minutes.The test utilizes antibody specific for adenovirus to selectively detect Adenovirus from human feces specimens.

      CLINICAL SENSITIVITY,SPECIFICITY AND ACCURACY

      The performance of the Adenovirus Rapid Test Device has been evaluated with 244 clinical specimens collected from children and young adults in comparison with latex agglutination method.The results show that the relative sensitivity of the Adenovirus Rapid Test?Device?is >99.9%and the relative specificity is 99.5%.

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